BRCA2 Antikörper (AA 450-500)

Produktnummer ABIN7449874

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BRCA2 in WB und IP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für BRCA2 Antikörper (AA 450-500) (ABIN7449874)

Target: BRCA2 (Breast Cancer 2, Early Onset (BRCA2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRCA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-BRCA2 Antikörper

Bindungsspezifität: AA 450-500

Verwendungszweck: Rabbit anti-BRCA2 Antibody, Affinity Purified

Aufreinigung: Affinity Purified

Immunogen: between AA 450 and 500

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

IP: 2 - 10 μg/mg lysate

WB: 1:10,000 - 1:25,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Haltbarkeit: 12 months

Details zu BRCA2

Target: BRCA2 (Breast Cancer 2, Early Onset (BRCA2))

Andere Bezeichnung: BRCA2

Hintergrund: Background: BRCA2 was identified as a gene with germline mutations that predisposes women to breast cancer. An important function of BRCA2 involves its direct interaction with RAD51 and the process of homologous recombination in DNA double strand break repair. BRCA2 and BRCA1 primary sequences are not similar, however the proteins exhibit similar patterns of expression and sub-cellular localization. Although the phenotype of disruptions of BRCA2 is similar to BRCA1, BRCA2 appears to possess functions distinct from BRCA1.

Gen-ID: 675

NCBI Accession: NP_000050

UniProt: P51587

Pathways: DNA Reparatur, M Phase, Maintenance of Protein Location