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BRCA2 Antikörper

BRCA2 Reaktivität: Human, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7234156
  • Target Alle BRCA2 Antikörper anzeigen
    BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
    Reaktivität
    • 56
    • 22
    • 20
    • 4
    • 2
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 55
    • 7
    Kaninchen
    Klonalität
    • 54
    • 8
    Polyklonal
    Konjugat
    • 31
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BRCA2 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 17
    • 13
    • 13
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Antigen Affinity Purification
    Immunogen
    Recombinant Human Breast cancer type 2 susceptibility protein
    Isotyp
    IgG
    Top Product
    Discover our top product BRCA2 Primärantikörper
  • Applikationshinweise
    WB 1:1000-1:3000 IHC 1:100-1:200 IF 1:100-1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.05 % Proclin300 and 50 % glycerol, pH 7.4.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
    Andere Bezeichnung
    BRCA2 (BRCA2 Produkte)
    Synonyme
    BRCC2 antikoerper, BROVCA2 antikoerper, FACD antikoerper, FAD antikoerper, FAD1 antikoerper, FANCB antikoerper, FANCD antikoerper, FANCD1 antikoerper, GLM3 antikoerper, PNCA2 antikoerper, 30169 antikoerper, BcDNA:SD25109 antikoerper, CG13583 antikoerper, CG13584 antikoerper, CG30169 antikoerper, Dmel\\CG30169 antikoerper, brca2 antikoerper, dmbrca2 antikoerper, fancd1 antikoerper, BRCA2 antikoerper, brcc2 antikoerper, brovca2 antikoerper, facd antikoerper, fad antikoerper, fad1 antikoerper, fancb antikoerper, AI256696 antikoerper, AW045498 antikoerper, Fancd1 antikoerper, RAB163 antikoerper, BRCA2, DNA repair associated antikoerper, Breast cancer 2, early onset homolog antikoerper, breast cancer 2, early onset antikoerper, BRCA2 antikoerper, Brca2 antikoerper, brca2 antikoerper, LOC584780 antikoerper
    Hintergrund
    Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.
    Molekulargewicht

    Observed_MW: 384 kDa

    Calculated_MW: 384 kDa

    UniProt
    P51587
    Pathways
    DNA Reparatur, M Phase, Maintenance of Protein Location
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