E2F1 Antikörper
Kurzübersicht für E2F1 Antikörper (ABIN7384438)
Target
Alle E2F1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Affinity Purified
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500-1:1000 IHC 1:20-1:100 IF 1:50-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 300 μg/mL
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Buffer
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- E2F1 (E2F Transcription Factor 1 (E2F1))
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Andere Bezeichnung
- E2F1
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Hintergrund
- E2F-1,RBAP1,RBBP3,RBP3,E2F1,The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain.
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Molekulargewicht
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Observed_MW: 70kDa
Calculated_MW: 47kDa
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Gen-ID
- 1869
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UniProt
- Q01094
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Pathways
- p53 Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagie
Target
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