SF3B1 Antikörper
Kurzübersicht für SF3B1 Antikörper (ABIN7384395)
Target
Alle SF3B1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Aufreinigung
- Affinity Purified
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-1:1000 IHC 1:50-1:100
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 300 μg/mL
-
Buffer
- 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
-
Andere Bezeichnung
- SF3B1
-
Hintergrund
- SF3B1,Hsh155,MDS,PRP10,PRPF10,SAP155,SF3b155,This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.
-
Molekulargewicht
-
Observed_MW: 146kDa
Calculated_MW: 146kDa
-
Gen-ID
- 23451
-
UniProt
- O75533
-
Pathways
- Chromatin Binding
Target
-