RAD21 Antikörper

Produktnummer ABIN7384393

Dieses Anti-RAD21-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von RAD21 in WB und IHC (p). Geeignet für Human und Hamster.

Kurzübersicht für RAD21 Antikörper (ABIN7384393)

Target: RAD21 (RAD21 Homolog (RAD21))

Reaktivität: Human, Hamster

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser RAD21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: R03-5I0

Produktdetails anti-RAD21 Antikörper

Aufreinigung: Affinity Purified

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000 IHC 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 300 μg/mL

Buffer: 50 mM Tris-Glycine( pH 7.4), 0.15M NaCl, 40 % Glycerol, 0.01 % Sodium azide and 0.05 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RAD21

Target: RAD21 (RAD21 Homolog (RAD21))

Andere Bezeichnung: Rad21

Hintergrund: MGS,HR21,MCD1,NXP1,SCC1,CDLS4,hHR21,HRAD21,RAD21, also named as Nuclear matrix protein 1, is a 631 amino acid protein, which belongs to the rad21 family. The calculated molecular weight of RAD21 is 72 kDa, but the phosphorylated RAD21 is about 120 kDa. The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells

Molekulargewicht:

Observed_MW: 130kDa

Calculated_MW: 72kDa

Gen-ID: 5885

UniProt: O60216

Pathways: Positive Regulation of Endopeptidase Activity