GLI1 Antikörper (AA 200-300)
Kurzübersicht für GLI1 Antikörper (AA 200-300) (ABIN7271533)
Target
Alle GLI1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 200-300
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Verwendungszweck
- GLI1 Rabbit pAb
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Sequenz
- EKPYMCEHEG CSKAFSNASD RAKHQNRTHS NEKPYVCKLP GCTKRYTDPS SLRKHVKTVH GPDAHVTKRH RGDGPLPRAP SISTVEPKRE REGGPIREES R
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 200-300 of human GLI1 (NP_001153517.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- GLI1 (Zinc Finger Protein GLI1 (GLI1))
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Andere Bezeichnung
- GLI1
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Hintergrund
- This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.,GLI1,GLI,Epigenetics & Nuclear Signaling,Transcription Factors,Cancer,Tumor suppressors,Signal Transduction,Cell Biology & Developmental Biology,Hedgehog Signaling Pathway,Neuroscience,Stem Cells,GLI1
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Molekulargewicht
- 104kDa/113kDa/117kDa
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Gen-ID
- 2735
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UniProt
- P08151
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Pathways
- Hedgehog Signalweg, Dopaminergic Neurogenesis
Target
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