TRIM5 Antikörper (AA 100-200)

Produktnummer ABIN7270992

Dieses Anti-TRIM5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TRIM5 in WB. Geeignet für Human.

Kurzübersicht für TRIM5 Antikörper (AA 100-200) (ABIN7270992)

Target: TRIM5 (Tripartite Motif Containing 5 (TRIM5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TRIM5 Antikörper

Bindungsspezifität: AA 100-200

Verwendungszweck: TRIM5 Rabbit pAb

Sequenz: EKLLLFCQED GKVICWLCER SQEHRGHHTF LTEEVAREYQ VKLQAALEML RQKQQEAEEL EADIREEKAS WKTQIQYDKT NVLADFEQLR DILDWEESNE L

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TRIM5 (NP_149083.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TRIM5

Target: TRIM5 (Tripartite Motif Containing 5 (TRIM5))

Andere Bezeichnung: TRIM5

Hintergrund: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.,TRIM5,RNF88,TRIM5alpha,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,Immunology & Inflammation,TRIM5

Molekulargewicht: 29kDa/31kDa/37kDa/40kDa/46kDa/56kDa

Gen-ID: 85363

UniProt: Q9C035

Pathways: Activation of Innate immune Response