This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
TLE1
(Transducin-Like Enhancer of Split 1 (E(sp1) Homolog, Drosophila) (TLE1))
Andere Bezeichnung
TLE1
Hintergrund
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. Enhances FOXG1/BF-1- and HES1-mediated transcriptional repression (By similarity. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.,ESG, ESG1, GRG1,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,Stem Cells,Wnt/β-Catenin Signaling Pathway,TLE1