SF3B1 Antikörper (pThr313)
Kurzübersicht für SF3B1 Antikörper (pThr313) (ABIN7270541)
Target
Alle SF3B1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pThr313
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Verwendungszweck
- Phospho-SF3B1-T313 Rabbit pAb
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Sequenz
- AETPR
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Phosphorylated Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthetic phosphorylated peptide around T313 of human SF3B1 (NP_036565.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- SF3B1 (Splicing Factor 3b, Subunit 1, 155kDa (SF3B1))
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Andere Bezeichnung
- SF3B1
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Hintergrund
- This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.,SF3B1,Hsh155,MDS,PRP10,PRPF10,SAP155,SF3b155,Epigenetics & Nuclear Signaling,RNA Binding,Protein phosphorylation,SF3B1
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Molekulargewicht
- 16kDa/145kDa
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Gen-ID
- 23451
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UniProt
- O75533
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Pathways
- Chromatin Binding
Target
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