STAT1 Antikörper

Produktnummer ABIN7270303

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch STAT1 in WB und IP. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für STAT1 Antikörper (ABIN7270303)

Target: STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser STAT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-STAT1 Antikörper

Verwendungszweck: STAT1 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human STAT1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu STAT1

Target: STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))

Andere Bezeichnung: STAT1

Hintergrund: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008],CANDF7,IMD31A,IMD31B,IMD31C,ISGF-3,STAT91,STAT1 alpha,STAT1,Apoptosis,Apoptosis_Inhibition of Apoptosis,Cancer,Cell Biology & Developmental Biology,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Protein phosphorylation,Signal Transduction,Transcription Factors,STAT1

Molekulargewicht: 87kDa

Gen-ID: 6772

UniProt: P42224

Pathways: JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events