SQSTM1 Antikörper (pSer349)
Kurzübersicht für SQSTM1 Antikörper (pSer349) (ABIN7270206)
Target
Alle SQSTM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer349
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Verwendungszweck
- Phospho-SQSTM1/p62-S349 Rabbit pAb
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Phosphorylated Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A phospho specific peptide corresponding to residues surrounding S349 of human SQSTM1/p62
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- SQSTM1 (Sequestosome 1 (SQSTM1))
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Andere Bezeichnung
- SQSTM1
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Hintergrund
- This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.,SQSTM1,A170,DMRV,FTDALS3,NADGP,OSIL,PDB3,ZIP3,p60,p62,p62B,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Cardiovascular,Heart,Mitochondrial Control of Autophagy,SQSTM1
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Molekulargewicht
- 38kDa/47kDa
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Gen-ID
- 8878
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UniProt
- Q13501
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Pathways
- NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie
Target
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