HIF1AN Antikörper
Kurzübersicht für HIF1AN Antikörper (ABIN7267820)
Target
Alle HIF1AN Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Verwendungszweck
- [KO Validated] HIF1AN/FIH1 Rabbit mAb
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Kreuzreaktivität
- Human
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Produktmerkmale
- Monoclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthesized peptide derived from human HIF1AN/FIH1
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Isotyp
- IgG
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anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 31-349) antibody
HIF1AN Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 1-349) antibodyHIF1AN Reaktivität: Human WB, ELISA, IF, IP Wirt: Maus Monoclonal 1D8 unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 2-254) antibodyHIF1AN Reaktivität: Human WB, ELISA, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 1-349) antibodyHIF1AN Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) antibodyKD Validated HIF1AN Reaktivität: Human WB, ICC, FACS Wirt: Kaninchen Monoclonal 23GB6385 unconjugated Recombinant Antibody
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) antibodyHIF1AN Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (N-Term) antibodyHIF1AN Reaktivität: Human, Kaninchen, Pferd WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 1-349) antibodyHIF1AN Reaktivität: Human WB, IF Wirt: Maus Monoclonal 931CT3-1-1 unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (AA 286-316), (C-Term) antibodyHIF1AN Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB10747 unconjugated
anti-Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN) (C-Term) antibodyHIF1AN Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- HIF1AN (Hypoxia Inducible Factor 1, alpha Subunit Inhibitor (HIF1AN))
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Andere Bezeichnung
- HIF1AN
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Hintergrund
- Hydroxylates HIF-1 alpha at 'Asn-803' in the C-terminal transactivation domain (CAD. Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins. Also hydroxylates Asp and His residues within ARDs of ANK1 and TNKS2, respectively. Negatively regulates NOTCH1 activity, accelerating myogenic differentiation. Positively regulates ASB4 activity, promoting vascular differentiation.,FIH1,Cancer,Cardiovascular,Epigenetics & Nuclear Signaling,Hypoxia,Hypoxia_HIF,Invasion and Metastasis,HIF1AN
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Molekulargewicht
- 40kDa
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Gen-ID
- 55662
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UniProt
- Q9NWT6
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
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