Cyclin H Antikörper

Produktnummer ABIN7266569

Der Kaninchen Monoklonal Anti-Cyclin H-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, Cyclin H in Proben von Human zu detektieren.

Kurzübersicht für Cyclin H Antikörper (ABIN7266569)

Target: Cyclin H (CCNH)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Cyclin H Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Cyclin H Antikörper

Verwendungszweck: Cyclin H Rabbit mAb

Kreuzreaktivität: Human, Maus

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human Cyclin H

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Cyclin H

Target: Cyclin H (CCNH)

Andere Bezeichnung: CCNH

Hintergrund: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Nov 2010],CAK, CycH, p34, p37,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Cyclins,DNA Damage & Repair,Epigenetics & Nuclear Signaling,CCNH

Molekulargewicht: 38kDa

Gen-ID: 902

UniProt: P51946

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, M Phase