Cyclin H Antikörper (AA 221-323)

Produktnummer ABIN734408

Produktdetails anti-Cyclin H Antikörper

Target: Cyclin H (CCNH)

Bindungsspezifität: AA 221-323

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin H Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Cyclin H

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu Cyclin H

Target: Cyclin H (CCNH)

Andere Bezeichnung: Cyclin H (CCNH Produkte)

Synonyme: zgc:114132 antikoerper, cak antikoerper, p34 antikoerper, p37 antikoerper, Cych antikoerper, ACYPI004637 antikoerper, ccnh antikoerper, Cyclin-H antikoerper, 142767_at antikoerper, CG7405 antikoerper, Dmel\\CG7405 antikoerper, CAK antikoerper, 6330408H09Rik antikoerper, AI661354 antikoerper, AV102684 antikoerper, AW538719 antikoerper, ccnh-A antikoerper, cyclin H antikoerper, cyclin-H antikoerper, Cyclin H antikoerper, CYclin H antikoerper, cyclin H L homeolog antikoerper, CCNH antikoerper, ccnh antikoerper, LOC5577539 antikoerper, Cych antikoerper, CycH antikoerper, cyh-1 antikoerper, Ccnh antikoerper, ccnh.L antikoerper

Hintergrund:

Synonyms: CAK, p34, p37, CycH, Cyclin-H, MO15-associated protein, CCNH

Background: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

Gen-ID: 902

UniProt: P51946

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, M Phase