Girdin Antikörper (AA 1571-1870)
Kurzübersicht für Girdin Antikörper (AA 1571-1870) (ABIN7266446)
Target
Alle Girdin (CCDC88A) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 1571-1870
-
Verwendungszweck
- CCDC88A Rabbit pAb
-
Sequenz
- DDSSTGSRVH ASRPASLDSG RTSTSNSNNN ASLHEVKAGA VNNQSRPQSH SSGEFSLLHD HEAWSSSGSS PIQYLKRQTR SSPVLQHKIS ETLESRHHKI KTGSPGSEVV TLQQFLEESN KLTSVQIKSS SQENLLDEVM KSLSVSSDFL GKDKPVSCGL ARSVSGKTPG DFYDRRTTKP EFLRPGPRKT EDTYFISSAG KPTPGTQGKI KLVKESSLSR QSKDSNPYAT LPRASSVIST AEGTTRRTSI HDFLTKDSRL PISVDSPPAA ADSNTTAASN VDKVQESRNS KSRSREQQSS
-
Kreuzreaktivität
- Human
-
Produktmerkmale
- Polyclonal Antibodies
-
Aufreinigung
- Affinity purification
-
Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1571-1870 of human CCDC88A (NP_001129069.1).
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB,1:500 - 1:2000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
-
Andere Bezeichnung
- CCDC88A
-
Hintergrund
- This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,CCDC88A,APE,GIRDIN,GIV,GRDN,HkRP1,KIAA1212,PEHO,girdin,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Microtubules,Neuroscience,CCDC88A
-
Molekulargewicht
- 207kDa/212kDa/215kDa/216kDa
-
Gen-ID
- 55704
-
UniProt
- Q3V6T2
Target
-