Girdin Antikörper

Produktnummer ABIN7238657

Produktdetails anti-Girdin Antikörper

Target: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Girdin Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Synthetic peptide of human CCDC88A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Girdin

Target: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Andere Bezeichnung: CCDC88A (CCDC88A Produkte)

Synonyme: APE antikoerper, GIRDIN antikoerper, GIV antikoerper, GRDN antikoerper, HkRP1 antikoerper, KIAA1212 antikoerper, A430106J12Rik antikoerper, AI848406 antikoerper, Ape antikoerper, C130096N06Rik antikoerper, C330012F17Rik antikoerper, D130005J21Rik antikoerper, Girdin antikoerper, Giv antikoerper, Grdn antikoerper, Hkrp1 antikoerper, DKFZp459N1815 antikoerper, RGD1306694 antikoerper, coiled-coil domain containing 88A antikoerper, coiled coil domain containing 88A antikoerper, CCDC88A antikoerper, Ccdc88a antikoerper

Hintergrund: This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

NCBI Accession: NP_001129069

UniProt: Q3V6T2