GLI1 Antikörper (AA 460-490)

Produktnummer ABIN7228664

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GLI1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für GLI1 Antikörper (AA 460-490) (ABIN7228664)

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GLI1 Antikörper

Bindungsspezifität: AA 460-490

Verwendungszweck: Rabbit Anti-GLI-1 Polyclonal Antibody

Spezifität: This antibody detects endogenous levels of GLI-1

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GLI-1 protein at AA range: 460-490

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu GLI1

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Andere Bezeichnung: GLI-1

Hintergrund: Zinc finger protein GLI1, Glioma-associated oncogene, Oncogene GLIGLI1 encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 120kD

Gen-ID: 2735

UniProt: P08151

Pathways: Hedgehog Signalweg, Dopaminergic Neurogenesis