TLR5 Antikörper (AA 730-810)

Produktnummer ABIN7231828

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch TLR5 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für TLR5 Antikörper (AA 730-810) (ABIN7231828)

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TLR5 Antikörper

Bindungsspezifität: AA 730-810

Verwendungszweck: TLR5 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of TLR5 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human TLR5 protein at AA range: 730-810

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu TLR5

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Andere Bezeichnung: TLR5

Hintergrund: Rabbit Anti-TLR5 Polyclonal Antibody,Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3, TLR5, TIL3, Homo sapiens (Human),TLR5 encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by TLR5 recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in TLR5 have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.,TLR5

Molekulargewicht: observerd band 94kDa

Gen-ID: 7100

UniProt: O60602

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades