SPHK2 Antikörper

Produktnummer ABIN7223680

Der Kaninchen Polyklonal Anti-SPHK2 Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, SPHK2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SPHK2 Antikörper (ABIN7223680)

Target: SPHK2 (Sphingosine Kinase 2 (SPHK2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPHK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SPHK2 Antikörper

Verwendungszweck: SphK2 Polyclonal Antibody

Spezifität: SphK2 Polyclonal Antibody detects endogenous levels of SphK2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human SphK2 around the non-phosphorylation site of T614

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu SPHK2

Target: SPHK2 (Sphingosine Kinase 2 (SPHK2))

Andere Bezeichnung: SphK2

Hintergrund: Rabbit Anti-SphK2 Polyclonal Antibody,SPHK2, Sphingosine kinase 2, SK 2, SPK 2,SPHK2 (sphingosine kinase 2) encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for SPHK2.,Sphingosine kinase 2

Molekulargewicht: observerd band 70kDa

Gen-ID: 56848

UniProt: Q9NRA0

Pathways: VEGF Signaling