STAT4 Antikörper

Produktnummer ABIN7217140

Der Kaninchen Polyklonal anti-STAT4 Antikörper wird verwendet zum Nachweis von STAT4 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, ELISA, IP und IF.

Kurzübersicht für STAT4 Antikörper (ABIN7217140)

Target: STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STAT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Produktdetails anti-STAT4 Antikörper

Verwendungszweck: Rabbit Anti-Stat4 Polyclonal Antibody

Spezifität: Stat4 Polyclonal Antibody detects endogenous levels of Stat4 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Stat4 around the non-phosphorylation site of Y693

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IP 2-5 μg:mg lysate,ELISA 1:5000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu STAT4

Target: STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))

Andere Bezeichnung: Stat4

Hintergrund: STAT4, Signal transducer and activator of transcription 4Signal transducer and activator of transcription 4 encoded by STAT4 is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.

Molekulargewicht: 85kD

Gen-ID: 6775

UniProt: Q14765

Pathways: JAK-STAT Signalweg