STAT4 Antikörper (AA 600-700)

Produktnummer ABIN1682909

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch STAT4 in WB, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für STAT4 Antikörper (AA 600-700) (ABIN1682909)

Target: STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STAT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-STAT4 Antikörper

Bindungsspezifität: AA 600-700

Sequenz: SESHLGGITF TWVDHSESGE VRFHSVEPYN KGRLSALPFA DILRDYKVIM AENIPENPLK YLYPDIPKDK AFGKHYSSQP CEVSRPTERG DKGYVPSVFI P

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 600-700 of human STAT4 (NP_001230764.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu STAT4

Target: STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))

Andere Bezeichnung: STAT4

Hintergrund: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.,STAT4,SLEB11,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,ErbB-HER Signaling Pathway,Immunology & Inflammation,IL-6 Receptor Signaling Pathway,STAT4

Molekulargewicht: 85 kDa

Gen-ID: 6775

UniProt: Q14765

Pathways: JAK-STAT Signalweg