STAT4 Antikörper
Kurzübersicht für STAT4 Antikörper (ABIN1681118)
Target
Alle STAT4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Monoclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthesized peptide derived from human STAT4
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
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Andere Bezeichnung
- STAT4
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Hintergrund
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011],SLEB11,Epigenetics & Nuclear Signaling,ErbB-HER Signaling Pathway,IL-6 Receptor Signaling Pathway,Immunology & Inflammation,Protein phosphorylation,Signal Transduction,Transcription Factors,STAT4
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Molekulargewicht
- 86 kDa
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Gen-ID
- 6775
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UniProt
- Q14765
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Pathways
- JAK-STAT Signalweg
Target
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