RGS1 Antikörper (AA 90-170)

Produktnummer ABIN7216822

Dieser Anti-RGS1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von RGS1 in WB, ELISA und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für RGS1 Antikörper (AA 90-170) (ABIN7216822)

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RGS1 Antikörper

Bindungsspezifität: AA 90-170

Verwendungszweck: RGS1 Polyclonal Antibody

Spezifität: RGS1 Polyclonal Antibody detects endogenous levels of RGS1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human RGS1 at AA range: 90-170

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu RGS1

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Andere Bezeichnung: RGS1

Hintergrund: Rabbit Anti-RGS1 Polyclonal Antibody,RGS1, 1R20, BL34, IER1, Regulator of G-protein signaling 1, RGS1, B-cell activation protein BL34, Early response protein 1R20,RGS1 encodes a member of the regulator of G-protein signalling family. Regulator of G-protein signaling 1 is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.,Regulator of G-protein signaling 1

Molekulargewicht: observerd band 22kDa

Gen-ID: 5996

UniProt: Q08116

Pathways: MAPK Signalweg, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events