RGS1 Antikörper (AA 118-167)

Produktnummer ABIN1535285

Der Kaninchen Polyklonal anti-RGS1 Antikörper (ABIN1535285) detektiert spezifisch RGS1 in WB, ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für RGS1 Antikörper (AA 118-167) (ABIN1535285)

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-RGS1 Antikörper

Bindungsspezifität: AA 118-167

Verwendungszweck: RGS1 Antibody

Spezifität: RGS1 Polyclonal Antibody detects endogenous levels of RGS1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human RGS1. AA range:118-167

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu RGS1

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Andere Bezeichnung: RGS1

Hintergrund:

Synonyms: RGS1, 1R20, BL34, IER1, Regulator of G-protein signaling 1, RGS1, B-cell activation protein BL34, Early response protein 1R20

Background: This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq, Jul 2008],

Gene Name: RGS1

Protein Name: Regulator of G-protein signaling 1

Molekulargewicht: 22 kDa

Gen-ID: 5996

OMIM: 600323

UniProt: Q08116

Pathways: MAPK Signalweg, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events