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RAD51 Homolog B Antikörper (AA 180-260)

Dieser Anti-RAD51 Homolog B Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von RAD51 Homolog B in WB, ELISA und IHC (p). Geeignet für Human, Maus und Affe.
Produktnummer ABIN7223904

Kurzübersicht für RAD51 Homolog B Antikörper (AA 180-260) (ABIN7223904)

Target

Alle RAD51 Homolog B (Rad51B) Antikörper anzeigen
RAD51 Homolog B (Rad51B)

Reaktivität

  • 14
  • 7
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Maus, Affe

Wirt

  • 12
  • 2
Kaninchen

Klonalität

  • 13
  • 1
Polyklonal

Konjugat

  • 14
Dieser RAD51 Homolog B Antikörper ist unkonjugiert

Applikation

  • 14
  • 6
  • 6
  • 4
  • 2
  • 2
  • 2
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 180-260

    Verwendungszweck

    Rad51B Polyclonal Antibody

    Spezifität

    Rad51B Polyclonal Antibody detects endogenous levels of Rad51B protein.

    Aufreinigung

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    Immunogen

    Synthesized peptide derived from the Internal region of human Rad51B at AA range: 180-260

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

    Kommentare

    Primary Antibody

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • Target

    RAD51 Homolog B (Rad51B)

    Andere Bezeichnung

    Rad51B

    Hintergrund

    Rabbit Anti-Rad51B Polyclonal Antibody,RAD51B, RAD51L1, REC2, DNA repair protein RAD51 homolog 2, R51H2, RAD51 homolog B, Rad51B, RAD51-like protein 1,The protein encoded by RAD51B (RAD51 paralog B) is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of RAD51B was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.,DNA repair protein RAD51 homolog 2

    Molekulargewicht

    observerd band 45kDa

    Gen-ID

    5890

    UniProt

    O15315

    Pathways

    DNA Reparatur
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