H2AFZ Antikörper (AA 1-30)

Produktnummer ABIN7227046

Der Kaninchen Polyklonal anti-H2AFZ Antikörper (ABIN7227046) detektiert spezifisch H2AFZ in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für H2AFZ Antikörper (AA 1-30) (ABIN7227046)

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser H2AFZ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-H2AFZ Antikörper

Bindungsspezifität: AA 1-30

Verwendungszweck: Rabbit Anti-Histone H2A.Z Polyclonal Antibody

Spezifität: The antibody detects endogenous Histone H2A.Z.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic peptide from human protein at AA range: 1-30

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu H2AFZ

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Andere Bezeichnung: Histone H2A.Z

Hintergrund: Histone H2A.Z, H2A/zHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. H2AFZ (H2A histone family member Z) encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.

Molekulargewicht: 20kD

Gen-ID: 3015

UniProt: P0C0S5

Pathways: Telomere Maintenance