H2AFZ Antikörper (C-Term)

Produktnummer ABIN655184

Der Kaninchen Polyklonal anti-H2AFZ Antikörper wird verwendet zum Nachweis von H2AFZ in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für H2AFZ Antikörper (C-Term) (ABIN655184)

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser H2AFZ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB20139

Produktdetails anti-H2AFZ Antikörper

Bindungsspezifität: AA 59-86, C-Term

Homologie: B, E, C, Zf, D, M, Rb, X, Rat, Sh

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This H2AFZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-86 amino acids from the C-terminal region of human H2AFZ.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu H2AFZ

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Andere Bezeichnung: H2AFZ

Hintergrund: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq].

Molekulargewicht: 13553

Gen-ID: 3015

NCBI Accession: NP_002097

UniProt: P0C0S5

Pathways: Telomere Maintenance