FZD7 Antikörper (AA 20-100)

Produktnummer ABIN7214956

Der Kaninchen Polyklonal Anti-FZD7 Antikörper wurde für WB, ELISA und IF validiert. Er ist geeignet, FZD7 in Proben von Human und Maus zu detektieren.

Kurzübersicht für FZD7 Antikörper (AA 20-100) (ABIN7214956)

Target: FZD7 (Frizzled Family Receptor 7 (FZD7))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FZD7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-FZD7 Antikörper

Bindungsspezifität: AA 20-100

Verwendungszweck: Frizzled-7 Polyclonal Antibody

Spezifität: Frizzled-7 Polyclonal Antibody detects endogenous levels of Frizzled-7 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human Frizzled-7 at AA range: 20-100

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu FZD7

Target: FZD7 (Frizzled Family Receptor 7 (FZD7))

Andere Bezeichnung: Frizzled-7

Hintergrund: Rabbit Anti-Frizzled-7 Polyclonal Antibody,FZD7, Frizzled-7, Fz-7, hFz7, FzE3,Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. Frizzled-7 contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.,Frizzled-7

Molekulargewicht: observerd band 64kDa

Gen-ID: 8324

UniProt: O75084

Pathways: WNT Signalweg, Stem Cell Maintenance