EPH Receptor B4 Antikörper (AA 540-620)

Produktnummer ABIN7220308

Der Kaninchen Polyklonal anti-EPH Receptor B4 Antikörper wird verwendet zum Nachweis von EPH Receptor B4 in Proben von Human und Maus. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für EPH Receptor B4 Antikörper (AA 540-620) (ABIN7220308)

Target: EPH Receptor B4 (EPHB4)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor B4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-EPH Receptor B4 Antikörper

Bindungsspezifität: AA 540-620

Verwendungszweck: Rabbit Anti-EphB4 Polyclonal Antibody

Spezifität: EphB4 Polyclonal Antibody detects endogenous levels of EphB4 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human EphB4 at AA range: 540-620

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu EPH Receptor B4

Target: EPH Receptor B4 (EPHB4)

Andere Bezeichnung: EphB4

Hintergrund: EPHB4, HTK, MYK1, TYRO11, Ephrin type-B receptor 4, Hepatoma transmembrane kinase, Tyrosine-protein kinase TYRO11Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The EPH receptor B4 encoded by EPHB4 binds to ephrin-B2 and plays an essential role in vascular development.

Molekulargewicht: 108kD

Gen-ID: 2050

UniProt: P54760

Pathways: RTK Signalweg