DR4 Antikörper (AA 370-450)

Produktnummer ABIN7214618

Dieser Anti-DR4 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von DR4 in WB, ELISA und IF. Geeignet für Human und Affe.

Kurzübersicht für DR4 Antikörper (AA 370-450) (ABIN7214618)

Target: DR4 (Drought-Repressed 4 Protein (DR4))

Reaktivität: Human, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DR4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-DR4 Antikörper

Bindungsspezifität: AA 370-450

Verwendungszweck: DR4 Polyclonal Antibody

Spezifität: DR4 Polyclonal Antibody detects endogenous levels of DR4 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human DR4 at AA range: 370-450

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu DR4

Target: DR4 (Drought-Repressed 4 Protein (DR4))

Andere Bezeichnung: DR4

Hintergrund: Rabbit Anti-DR4 Polyclonal Antibody,TNFRSF10A, APO2, DR4, TRAILR1, Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAIL-R1, CD antigen CD261,TNF receptor superfamily member 10a encoded by TNFRSF10A is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.,Tumor necrosis factor receptor superfamily member 10A

Molekulargewicht: observerd band 50kDa

Gen-ID: 8797

UniProt: O00220

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity