CDK7 Antikörper (pThr170)

Produktnummer ABIN7218924

Dieser Anti-CDK7 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von CDK7 in WB, ELISA und IHC (p). Geeignet für Human und Maus.

Kurzübersicht für CDK7 Antikörper (pThr170) (ABIN7218924)

Target: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CDK7 Antikörper

Bindungsspezifität: pThr170

Verwendungszweck: Cdk7 (phospho Thr170) Polyclonal Antibody

Spezifität: Phospho-Cdk7 (T170) Polyclonal Antibody detects endogenous levels of Cdk7 protein only when phosphorylated at T170.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Cdk7 Phospho-Thr170

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu CDK7

Target: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Andere Bezeichnung: Cdk7

Hintergrund: Rabbit Anti-Cdk7 (phospho Thr170) Polyclonal Antibody,CDK7, CAK, CAK1, CDKN7, MO15, STK1, Cyclin-dependent kinase 7, 39 kDa protein kinase, p39 Mo15, CDK-activating kinase 1, Cell division protein kinase 7, Serine/threonine-protein kinase 1, TFIIH basal transcription factor complex kinase subunit,The cyclin dependent kinase 7 encoded by CDK7 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.,Cyclin-dependent kinase 7

Molekulargewicht: observerd band 40kDa

Gen-ID: 1022

UniProt: P50613

Pathways: Zellzyklus, DNA Reparatur, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase