Calnexin Antikörper (pSer583)
Kurzübersicht für Calnexin Antikörper (pSer583) (ABIN7212898)
Target
Alle Calnexin (CANX) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer583
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Verwendungszweck
- Calnexin (phospho Ser583) Polyclonal Antibody
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Spezifität
- Phospho-Calnexin (S583) Polyclonal Antibody detects endogenous levels of Calnexin protein only when phosphorylated at S583.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from human Calnexin Phospho-Ser583
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.
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Kommentare
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Primary Antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Calnexin (CANX)
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Andere Bezeichnung
- Calnexin
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Hintergrund
- Rabbit Anti-Calnexin (phospho Ser583) Polyclonal Antibody,CANX, Calnexin, IP90, Major histocompatibility complex class I antigen-binding protein p88, p90,CANX encodes a member of the calnexin family of molecular chaperones. Calnexin is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described,Calnexin
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Molekulargewicht
- observerd band 90kDa
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Gen-ID
- 821
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UniProt
- P27824
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Pathways
- MAPK Signalweg, Thyroid Hormone Synthesis
Target
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