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NCKAP1 Antikörper (AA 1001-1132) (Cy5.5)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NCKAP1 in WB. Er zeigt eine Reaktivität gegenüber Maus.
Produktnummer ABIN715741

Kurzübersicht für NCKAP1 Antikörper (AA 1001-1132) (Cy5.5) (ABIN715741)

Target

Alle NCKAP1 Antikörper anzeigen
NCKAP1 (NCK Associated Protein 1 (NCKAP1))

Reaktivität

  • 28
  • 26
  • 11
Maus

Wirt

  • 41
  • 1
Kaninchen

Klonalität

  • 42
Polyklonal

Konjugat

  • 17
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NCKAP1 Antikörper ist konjugiert mit Cy5.5

Applikation

  • 31
  • 13
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 14
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1001-1132

    Kreuzreaktivität

    Maus

    Homologie

    Human,Rat,Dog,Cow,Pig,Horse,Chicken,Guinea Pig

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human NCKAP1L

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    NCKAP1 (NCK Associated Protein 1 (NCKAP1))

    Andere Bezeichnung

    NCKAP1

    Hintergrund

    Synonyms: NCK associated protein 1, NCK associated protein 1, Membrane associated protein HEM2, Membrane-associated protein HEM-2, NAP 1, NAP1, NAP125, NCK associated protein, Nck-associated protein 1, Nckap1, NCKP1_HUMAN, p125Nap1.

    Background: NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease.

    Gen-ID

    10787

    UniProt

    P55160

    Pathways

    RTK Signalweg, Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis
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