NCKAP1 Antikörper

Produktnummer ABIN7191586

Produktdetails anti-NCKAP1 Antikörper

Target: NCKAP1 (NCK Associated Protein 1 (NCKAP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCKAP1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of Human NCKAP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:1000-1:2000, IHC:1:25-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu NCKAP1

Target: NCKAP1 (NCK Associated Protein 1 (NCKAP1))

Andere Bezeichnung: NCKAP1 (NCKAP1 Produkte)

Synonyme: HEM2 antikoerper, NAP1 antikoerper, NAP125 antikoerper, p125Nap1 antikoerper, C79304 antikoerper, H19 antikoerper, Hem-2 antikoerper, Hem2 antikoerper, Nap1 antikoerper, mKIAA0587 antikoerper, mh19 antikoerper, NCK associated protein 1 antikoerper, NCK-associated protein 1 antikoerper, NCK-associated protein 1 L homeolog antikoerper, NCKAP1 antikoerper, Nckap1 antikoerper, nckap1.L antikoerper

Hintergrund:

Background: NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease.

Aliases: FLJ11291 antibody, KIAA0587 antibody, Membrane associated protein HEM2 antibody, Membrane-associated protein HEM-2 antibody, MGC8981 antibody, NAP 1 antibody, NAP1 antibody, NAP125 antibody, NCK associated protein 1 antibody, NCK associated protein antibody, Nck-associated protein 1 antibody, Nckap1 antibody, NCKP1_HUMAN antibody, OTTHUMP00000163460 antibody, OTTHUMP00000163461 antibody, p125Nap1 antibody

UniProt: Q9Y2A7

Pathways: RTK Signalweg, Tube Formation, Asymmetric Protein Localization, Embryonic Body Morphogenesis