MDM2 Antikörper (AA 26-169)
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- Target Alle MDM2 Antikörper anzeigen
- MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
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Bindungsspezifität
- AA 26-169
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MDM2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Verwendungszweck
- MDM2 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human MDM2 (AA: 26-169) expressed in E. Coli.
- Klon
- 3C1E3
- Isotyp
- IgG2b
- Top Product
- Discover our top product MDM2 Primärantikörper
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anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 101-200) antibody
MDM2 Reaktivität: Human WB, ELISA, IHC (p), RNAi, PLA Wirt: Maus Monoclonal 1A7 unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (Center) antibodyMDM2 Reaktivität: Human, Maus WB, IF, IHC (p), IP, ICC, ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 130-230) antibodyMDM2 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 141-176) antibodyMDM2 Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB7981 unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (pSer166) antibodyMDM2 Reaktivität: Human, Maus, Affe WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 393-424) antibodyMDM2 Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (pSer186) antibodyMDM2 Reaktivität: Human WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 26-169) antibodyMDM2 Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 4A8D12 unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) antibodyMDM2 Reaktivität: Human, Maus, Ratte, Affe WB, ELISA, IHC, IF, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2) (AA 200-430) antibodyMDM2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200-1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- MDM2 (Mdm2, p53 E3 Ubiquitin Protein Ligase Homolog (Mouse) (MDM2))
- Andere Bezeichnung
- MDM2 (MDM2 Produkte)
- Hintergrund
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Description:
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.
Aliases: HDMX, LSKB, hdm2, ACTFS
- Molekulargewicht
- 55.2kDa
- Gen-ID
- 4193
- UniProt
- Q00987
- Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Autophagie, Ubiquitin Proteasome Pathway
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