DMBT1 Antikörper

Produktnummer ABIN7190483

Der Kaninchen Polyklonal Anti-DMBT1-Antikörper wurde für IHC und ELISA validiert. Er ist geeignet, DMBT1 in Proben von Human zu detektieren.

Kurzübersicht für DMBT1 Antikörper (ABIN7190483)

Target: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DMBT1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-DMBT1 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of Human DMBT1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:1000-1:2000, IHC:1:10-1:50,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DMBT1

Target: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Andere Bezeichnung: DMBT1

Hintergrund:

Background: Loss of sequences from human chromosome 10q has been associated with the progression of human cancers. The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line. DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized. The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID). Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition. This indicates that DMBT1 may not be a classical tumor suppressor gene, but rather play a role in the interaction of tumor cells and the immune system.

Aliases: Apactin antibody, CRP antibody, CRP-[a] antibody, CRP-[b] antibody, CRP-ductin antibody, Crpd antibody, DBMT1 antibody, Deleted in malignant brain tumors 1 antibody, Deleted in malignant brain tumors 1 protein antibody, DMBT 1 antibody, DMBT1 antibody, DMBT1 prototype precursor antibody, DMBT1/6kb.1 protein precursor antibody, DMBT1/8kb.1 protein antibody, DMBT1/8kb.2 protein precursor antibody, DMBT1_HUMAN antibody, Ebnerin antibody, FLJ61058 antibody, Glycoprotein 300 antibody, Glycoprotein 340 antibody, Gp 340 antibody, Gp-340 antibody, gp300 antibody, GP340 antibody, Gp340 variant protein antibody, Hensin antibody, MGC164738 antibody, Mucin-like glycoprotein antibody, Muclin antibody, OTTHUMP00000020654 antibody, OTTHUMP00000020655 antibody, OTTHUMP00000020656 antibody, OTTHUMP00000020657 antibody, OTTHUMP00000020658 antibody, OTTHUMP00000020659 antibody, OTTHUMP00000020660 antibody, OTTHUMP00000020661 antibody, OTTHUMP00000020662 antibody, OTTHUMP00000020663 antibody, p80 antibody, Pancrin antibody, SAG antibody, Salivary agglutinin antibody, Surfactant pulmonary associated D binding protein antibody, Surfactant pulmonary associated protein D binding protein antibody, Surfactant pulmonary-associated D-binding protein antibody, Vomeroglandin antibody

UniProt: Q9UGM3

Pathways: Activation of Innate immune Response