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BAX Antikörper (Thr167)

BAX Reaktivität: Human WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7179980
  • Target Alle BAX Antikörper anzeigen
    BAX (BCL2-Associated X Protein (BAX))
    Bindungsspezifität
    • 32
    • 26
    • 18
    • 16
    • 15
    • 12
    • 10
    • 9
    • 8
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Thr167
    Reaktivität
    • 237
    • 151
    • 135
    • 45
    • 30
    • 25
    • 23
    • 18
    • 16
    • 11
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 149
    • 95
    • 3
    • 1
    Kaninchen
    Klonalität
    • 162
    • 86
    Polyklonal
    Konjugat
    • 127
    • 13
    • 11
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser BAX Antikörper ist unkonjugiert
    Applikation
    • 213
    • 92
    • 77
    • 56
    • 52
    • 52
    • 47
    • 35
    • 35
    • 12
    • 11
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Kreuzreaktivität
    Human, Maus
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    Synthesized non-phosphopeptide derived from Human Bax around the phosphorylation site of threonine 167 (F-G-T(p)-P-T).
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    WB:1:500-1:3000, IF:1:100-1:500,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    BAX (BCL2-Associated X Protein (BAX))
    Andere Bezeichnung
    BAX (BAX Produkte)
    Hintergrund

    Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.

    Oltvai Z.N., Cell 74:609-619(1993).
    Cuddeback S.M., J. Biol. Chem. 276:20559-20565(2001).
    Guo B., Nature 423:456-461(2003)

    Aliases: Apoptosis regulator BAX antibody, BAX antibody, Bax-protein antibody, BAX_HUMAN antibody, BAXA antibody, Baxdelta2G9 antibody, Baxdelta2G9omega antibody, Baxdelta2omega antibody, Bcl-2-like protein 4 antibody, BCL2 associated X protein antibody, BCL2 associated X protein omega antibody, BCL2 associated X protein transcript variant delta2 antibody, Bcl2-L-4 antibody, BCL2L4 antibody, membrane isoform alpha antibody

    UniProt
    Q07812
    Pathways
    p53 Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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