Hepcidin Antikörper

Produktnummer ABIN7178664

Der Kaninchen Polyklonal Anti-Hepcidin-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, Hepcidin in Proben von Human zu detektieren.

Kurzübersicht für Hepcidin Antikörper (ABIN7178664)

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Hepcidin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-Hepcidin Antikörper

Kreuzreaktivität: Human, Maus

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of Human HAMP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:2000, IHC:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Store at -20 °C or -80 °C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Hepcidin

Target: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Andere Bezeichnung: HAMP

Hintergrund:

Background: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure.

Aliases: Hamp antibody, HEPC antibody, HEPC_HUMAN antibody, Hepc20 antibody, Hepc25 antibody, HEPCIDIN antibody, Hepcidin 20 antibody, Hepcidin 25 antibody, Hepcidin antimicrobial peptide antibody, Hepcidin-20 antibody, Hepcidin25 antibody, HFE2 antibody, HFE2B antibody, LEAP 1 antibody, LEAP-1 antibody, LEAP1 antibody, Liver expressed antimicrobial peptide antibody, Liver-expressed antimicrobial peptide 1 antibody, PLTR antibody, Putative liver tumor regressor antibody

UniProt: P81172

Pathways: Hormone Activity, Transition Metal Ion Homeostasis