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WEE1 Antikörper (AA 45-177) (HRP)

Der Kaninchen Polyklonal Anti-WEE1-Antikörper wurde für ELISA validiert. Er ist geeignet, WEE1 in Proben von Human zu detektieren.
Produktnummer ABIN7175817

Kurzübersicht für WEE1 Antikörper (AA 45-177) (HRP) (ABIN7175817)

Target

Alle WEE1 Antikörper anzeigen
WEE1 (WEE1 Homolog (S. Pombe) (WEE1))

Reaktivität

  • 84
  • 48
  • 35
  • 2
Human

Wirt

  • 94
  • 5
  • 2
Kaninchen

Klonalität

  • 99
  • 2
Polyklonal

Konjugat

  • 47
  • 7
  • 7
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser WEE1 Antikörper ist konjugiert mit HRP

Applikation

  • 81
  • 47
  • 28
  • 28
  • 19
  • 16
  • 8
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
ELISA
  • Bindungsspezifität

    • 20
    • 15
    • 11
    • 9
    • 8
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 45-177

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human Wee1-like protein kinase protein (45-177AA)

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    WEE1 (WEE1 Homolog (S. Pombe) (WEE1))

    Andere Bezeichnung

    WEE1

    Hintergrund

    Background: Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on \'Tyr-15\'. Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase. Phosphorylation of cyclin B1-CDK1 occurs exclusively on \'Tyr-15\' and phosphorylation of monomeric CDK1 does not occur. Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated. A correlated decrease in protein level occurs at M/G1 phase, probably due to its degradation.

    Aliases: DKFZp686I18166 antibody, EC 2.7.10.2 antibody, FLJ16446 antibody, MGC105683 antibody, OTTHUMP00000231338 antibody, OTTHUMP00000231339 antibody, Wee 1 antibody, WEE 1 homolog 1 (S. pombe) antibody, WEE1 antibody, WEE1 homolog (S. pombe) antibody, Wee1 homolog antibody, WEE1 homolog S. pombe antibody, Wee1 like protein kinase antibody, Wee1 tyrosine kinase antibody, Wee1+ homolog antibody, Wee1+ S. pombe homolog antibody, WEE1, S. pombe, homolog of antibody, WEE1, somatic antibody, Wee1-like protein kinase antibody, WEE1_HUMAN antibody, WEE1A antibody, Wee1A kinase antibody, WEE1hu antibody

    UniProt

    P30291

    Pathways

    Zellzyklus, Mitotic G1-G1/S Phases, M Phase
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