SHP1 Antikörper (AA 1-597) (Biotin)

Produktnummer ABIN7174117

Dieses Anti-SHP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SHP1 in ELISA. Geeignet für Human.

Kurzübersicht für SHP1 Antikörper (AA 1-597) (Biotin) (ABIN7174117)

Target: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SHP1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-SHP1 Antikörper (Biotin)

Bindungsspezifität: AA 1-597

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Tyrosine-protein phosphatase non-receptor type 6 protein (1-597AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SHP1

Target: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Andere Bezeichnung: PTPN6

Hintergrund:

Background: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.

Aliases: 70Z-SHP antibody, EC 3.1.3.48 antibody, HCP antibody, HCPH antibody, Hematopoietic cell phosphatase antibody, Hematopoietic cell protein tyrosine phosphatase antibody, Hematopoietic cell protein-tyrosine phosphatase antibody, HPTP1C antibody, Protein tyrosine phosphatase 1C antibody, Protein tyrosine phosphatase non receptor type 6 antibody, Protein tyrosine phosphatase SHP1 antibody, Protein-tyrosine phosphatase 1C antibody, protein-tyrosine phosphatase SHP 1 antibody, Protein-tyrosine phosphatase SHP-1 antibody, PTN6_HUMAN antibody, PTP 1C antibody, PTP-1C antibody, PTP1C antibody, Ptpn6 antibody, SH PTP 1 antibody, SH PTP1 antibody, SH-PTP1 antibody, SHP 1 antibody, SHP 1L antibody, SHP1 antibody, SHP1L antibody, tyrosine protein phosphatase non receptor type 6 antibody, Tyrosine-protein phosphatase non-receptor type 6 antibody

UniProt: P29350

Pathways: JAK-STAT Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling