PARP3 Antikörper (AA 1-240)

Produktnummer ABIN7163751

Der Kaninchen Polyklonal Anti-PARP3-Antikörper wurde für ELISA, WB und IHC validiert. Er ist geeignet, PARP3 in Proben von Human zu detektieren.

Kurzübersicht für PARP3 Antikörper (AA 1-240) (ABIN7163751)

Target: PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARP3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PARP3 Antikörper

Bindungsspezifität: AA 1-240

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Poly [ADP-ribose] polymerase 3 protein (1-240AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PARP3

Target: PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

Andere Bezeichnung: PARP3

Hintergrund:

Background: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.

Aliases: ADP ribosyltransferase (NAD+, poly (ADP ribose) antibody, ADP ribosyltransferase diphtheria toxin like 3 antibody, ADPRT-3 antibody, ADPRT3 antibody, ADPRTL2 antibody, ADPRTL3 antibody, ARTD3 antibody, hPARP 3 antibody, hPARP-3 antibody, hPARP3 antibody, IRT 1 antibody, IRT1 antibody, NAD(+) ADP ribosyltransferase 3 antibody, NAD(+) ADP-ribosyltransferase 3 antibody, NAD+ ADP ribosyltransferase 3 antibody, pADPRT 3 antibody, pADPRT-3 antibody, pADPRT3 antibody, PARP 3 antibody, PARP-3 antibody, PARP3 antibody, PARP3_HUMAN antibody, Poly (ADP ribose) polymerase family, member 3 antibody, Poly (ADP ribose) synthetase 3 antibody, Poly [ADP-ribose] polymerase 3 antibody, Poly[ADP ribose] synthetase 3 antibody, Poly[ADP-ribose] synthase 3 antibody

UniProt: Q9Y6F1