MYD88 Antikörper (AA 1-282)
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- Target Alle MYD88 Antikörper anzeigen
- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
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Bindungsspezifität
- AA 1-282
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MYD88 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human Myeloid differentiation primary response protein MyD88 protein (1-282AA)
- Isotyp
- IgG
- Top Product
- Discover our top product MYD88 Primärantikörper
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- Applikationshinweise
- Recommended dilution: IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
- Andere Bezeichnung
- MYD88 (MYD88 Produkte)
- Synonyme
- MYD88D antikoerper, XMyD88 antikoerper, myd88d antikoerper, MGC84928 antikoerper, CG2078 antikoerper, DMMYD88 antikoerper, DmMyD88 antikoerper, DmMyd88 antikoerper, Dmel\\CG2078 antikoerper, EP(2)2535 antikoerper, Kra antikoerper, LD20892 antikoerper, MYD88 antikoerper, MyD88 antikoerper, Myd88F antikoerper, dMyD88 antikoerper, dMyd88 antikoerper, kra antikoerper, myd88 antikoerper, zgc:103541 antikoerper, GB12344 antikoerper, NV10640 antikoerper, myd88-a antikoerper, myd88-b antikoerper, myeloid differentiation primary response 88 antikoerper, myeloid differentiation primary response 88 S homeolog antikoerper, myeloid differentiation primary response gene 88 antikoerper, CG2078 gene product from transcript CG2078-RB antikoerper, myeloid differentiation primary response protein MyD88-A antikoerper, myeloid differentiation primary response protein MyD88 antikoerper, myeloid differentiation factor 88 antikoerper, myeloid differentiation primary response 88 L homeolog antikoerper, MYD88 antikoerper, myd88.S antikoerper, Myd88 antikoerper, myd88 antikoerper, LOC413194 antikoerper, LOC100118553 antikoerper, LOC575153 antikoerper, myd88.L antikoerper
- Hintergrund
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Background: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine.
Aliases: Mutant myeloid differentiation primary response 88 antibody, MYD 88 antibody, Myd88 antibody, MYD88_HUMAN antibody, MYD88D antibody, Myeloid differentiation marker 88 antibody, Myeloid differentiation primary response 88 antibody, Myeloid differentiation primary response gene (88) antibody, Myeloid differentiation primary response gene 88 antibody, Myeloid differentiation primary response gene antibody, Myeloid differentiation primary response protein MyD88 antibody, OTTHUMP00000161718 antibody, OTTHUMP00000208595 antibody, OTTHUMP00000209058 antibody, OTTHUMP00000209059 antibody, OTTHUMP00000209060 antibody
- UniProt
- Q99836
- Pathways
- NF-kappaB Signalweg, TLR Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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