PIK3R1 Antikörper (pTyr467) (Cy5)
-
- Target Alle PIK3R1 (PI3K p85a) Antikörper anzeigen
- PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))
-
Bindungsspezifität
- pTyr467
-
Reaktivität
- Human, Maus, Schwein
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser PIK3R1 Antikörper ist konjugiert mit Cy5
-
Applikation
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Kreuzreaktivität
- Human, Maus, Schwein
- Homologie
- Rat,Dog,Cow,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human PIK3R1 around the phosphorylation site of Tyr467 [RL(p-Y)EE]
- Isotyp
- IgG
- Top Product
- Discover our top product PI3K p85a Primärantikörper
-
-
- Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))
- Andere Bezeichnung
- PIK3R1 (PI3K p85a Produkte)
- Synonyme
- PI3CG antikoerper, PI3K antikoerper, PI3Kgamma antikoerper, PIK3 antikoerper, AGM7 antikoerper, GRB1 antikoerper, p85 antikoerper, p85-ALPHA antikoerper, PI3KA antikoerper, AA414921 antikoerper, C530050K14 antikoerper, p50alpha antikoerper, p55alpha antikoerper, p85alpha antikoerper, wu:fb65b05 antikoerper, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma antikoerper, phosphoinositide-3-kinase regulatory subunit 1 antikoerper, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta antikoerper, phosphoinositide-3-kinase, regulatory subunit 1 (alpha) antikoerper, PIK3CG antikoerper, PIK3R1 antikoerper, Pik3r1 antikoerper, Pik3cb antikoerper, pik3r1 antikoerper
- Hintergrund
-
Synonyms: PIK3R1phospho Y467, GRB1, p50 alpha, p55 alpha, p85 alpha, p85, Phosphatidylinositol 3 kinase associated p85 alpha, Phosphatidylinositol 3 kinase regulatory 1, Phosphatidylinositol 3 kinase regulatory alpha subunit, Phosphoinositide 3 kinase regulatory subunit polypeptide 1 p85 alpha, PI3 kinase p85 alpha subunit, PI3 kinase p85 subunit alpha, PI3K , PIK3R1, PtdIns 3 kinase p85 alpha.
Background: The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 alpha). p85 alpha is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 alpha is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.
- Gen-ID
- 5295
- Pathways
- T-Zell Rezeptor Signalweg, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, Warburg Effekt
-