ROR1 Antikörper (AA 30-391)

Produktnummer ABIN7156195

Dieses Anti-ROR1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ROR1 in ELISA und IHC. Geeignet für Human.

Kurzübersicht für ROR1 Antikörper (AA 30-391) (ABIN7156195)

Target: ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ROR1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-ROR1 Antikörper

Bindungsspezifität: AA 30-391

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Inactive tyrosine-protein kinase transmembrane receptor ROR1 protein (30-391AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:10-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ROR1

Target: ROR1 (Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1))

Andere Bezeichnung: ROR1

Hintergrund:

Background: Has very low kinase activity in vitro and is unlikely to function as a tyrosine kinase in vivo (PubMed:25029443). Receptor for ligand WNT5A which activate downstream NFkB signaling pathway and may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443, PubMed:27162350). In inner ear, crucial for spiral ganglion neurons to innervate auditory hair cells (PubMed:27162350).

Aliases: dJ537F10.1 antibody, Inactive tyrosine protein kinase transmembrane receptor ROR1 antibody, MGC99659 antibody, Neurotrophic tyrosine kinase antibody, Neurotrophic tyrosine kinase receptor related 1 antibody, Neurotrophic tyrosine kinase, receptor related 1 antibody, NTRKR1 antibody, OTTHUMP00000010573 antibody, OTTHUMP00000010574 antibody, OTTMUSP00000008344 antibody, Receptor tyrosine kinase like orphan receptor 1 antibody, receptor-related 1 antibody, RGD1559469 antibody, ROR 1 antibody, ROR1 antibody, ROR1_HUMAN antibody, RP11 24J23.1 antibody, Tyrosine kinase like orphan receptor 1 antibody, Tyrosine protein kinase transmembrane receptor ROR1 antibody, Tyrosine-protein kinase transmembrane receptor ROR1 antibody

UniProt: Q01973

Pathways: RTK Signalweg, WNT Signalweg, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha