EPH Receptor B4 Antikörper (AA 300-540)

Produktnummer ABIN7151868

Der Kaninchen Polyklonal Anti-EPH Receptor B4-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, EPH Receptor B4 in Proben von Human zu detektieren.

Kurzübersicht für EPH Receptor B4 Antikörper (AA 300-540) (ABIN7151868)

Target: EPH Receptor B4 (EPHB4)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor B4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-EPH Receptor B4 Antikörper

Bindungsspezifität: AA 300-540

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Ephrin type-B receptor 4 protein (300-540AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu EPH Receptor B4

Target: EPH Receptor B4 (EPHB4)

Andere Bezeichnung: EPHB4

Hintergrund:

Background: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.

Aliases: Ephb4 antibody, EPHB4_HUMAN antibody, Ephrin receptor EphB4 antibody, Ephrin type-B receptor 4 antibody, Hepatoma Transmembrane Kinase antibody, HTK antibody, MYK 1 antibody, MYK1 antibody, TYRO 11 antibody, TYRO11 antibody, Tyrosine-protein kinase receptor HTK antibody, Tyrosine-protein kinase TYRO11 antibody

UniProt: P54760

Pathways: RTK Signalweg