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DPP4 Antikörper (AA 473-588)

Der Kaninchen Polyklonal Anti-DPP4-Antikörper wurde für WB, IHC, IF und ELISA validiert. Er ist geeignet, DPP4 in Proben von Human zu detektieren.
Produktnummer ABIN7149984

Kurzübersicht für DPP4 Antikörper (AA 473-588) (ABIN7149984)

Target

Alle DPP4 Antikörper anzeigen
DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reaktivität

  • 140
  • 48
  • 48
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 92
  • 75
  • 17
  • 3
  • 1
Kaninchen

Klonalität

  • 101
  • 85
  • 1
Polyklonal

Konjugat

  • 97
  • 27
  • 16
  • 11
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DPP4 Antikörper ist unkonjugiert

Applikation

  • 90
  • 73
  • 63
  • 40
  • 34
  • 34
  • 32
  • 32
  • 6
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA
  • Bindungsspezifität

    • 11
    • 9
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 473-588

    Kreuzreaktivität

    Human, Ratte

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human Dipeptidyl peptidase 4 protein (473-588AA)

    Isotyp

    IgG
  • Applikationshinweise

    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

    Andere Bezeichnung

    DPP4

    Hintergrund

    Background: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

    Aliases: ADABP antibody, ADCP-2 antibody, ADCP2 antibody, Adenosine deaminase complexing protein 2 antibody, CD26 antibody, Dipeptidyl peptidase 4 antibody, Dipeptidyl peptidase 4 soluble form antibody, Dipeptidyl peptidase IV antibody, Dipeptidyl peptidase IV membrane form antibody, Dipeptidyl peptidase IV soluble form antibody, DPP IV antibody, DPP4 antibody, DPP4_HUMAN antibody, DPPIV antibody, T-cell activation antigen CD26 antibody, TP103 antibody

    UniProt

    P27487

    Pathways

    Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity
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