DPP4 Antikörper

Produktnummer ABIN457416

Produktdetails anti-DPP4 Antikörper

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DPP4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Spezifität: The mouse monoclonal antibody BA5b recognizes an extracellular epitope of CD26, a 110 kDa type II transmembrane glycoprotein, which is a peptidase expressed on mature thymocytes, T cells (especially activated), B cells, NK cells and macrophages.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: A human T cell clone

Klon: BA5b

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-2 μg/mL, positive control: human peripheral blood leukocytes.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu DPP4

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Andere Bezeichnung: CD26 (DPP4 Produkte)

Synonyme: ADABP antikoerper, ADCP2 antikoerper, CD26 antikoerper, DPPIV antikoerper, TP103 antikoerper, MGC81966 antikoerper, MOP9.8 antikoerper, MOP9_8 antikoerper, DPP4 antikoerper, si:ch73-2d23.3 antikoerper, Cd26 antikoerper, Dpp-4 antikoerper, THAM antikoerper, dipeptidyl peptidase 4 antikoerper, dipeptidyl-peptidase 4 S homeolog antikoerper, prolyl oligopeptidase family protein antikoerper, dipeptidyl-peptidase 4 antikoerper, dipeptidylpeptidase 4 antikoerper, DPP4 antikoerper, dpp4.S antikoerper, AT5G24260 antikoerper, dpp4 antikoerper, Dpp4 antikoerper

Hintergrund: Dipeptidyl peptidase 4,CD26, also known as dipeptidyl peptidase IV (DPP-IV), is a homodimeric cell surface serine peptidase that degradates IFN-gamma-induced cytokines, acts as a T cell costimulatory molecule, and participates in multiple immunopathological roles in leukocyte homing and inflammation. Alterations in its peptidase activity are characteristic of malignant transformation. The enzymatic activity increases dramatically with tumour grade and severity. CD26 is expressed in various blood cell types, but also e.g. in cells that are histogenetically related to activated fibroblasts. Alterations in CD26 density have been reported on circulating monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.,DPP4, TP103, ADCP-2, ADABP

Gen-ID: 1803

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity