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Cyclin H Antikörper (AA 261-319)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Cyclin H in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7148939

Kurzübersicht für Cyclin H Antikörper (AA 261-319) (ABIN7148939)

Target

Alle Cyclin H (CCNH) Antikörper anzeigen
Cyclin H (CCNH)

Reaktivität

  • 85
  • 48
  • 29
  • 7
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
Human

Wirt

  • 71
  • 16
Kaninchen

Klonalität

  • 64
  • 23
Polyklonal

Konjugat

  • 52
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
Dieser Cyclin H Antikörper ist unkonjugiert

Applikation

  • 56
  • 33
  • 20
  • 19
  • 16
  • 7
  • 6
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 12
    • 11
    • 8
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 261-319

    Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human Cyclin-H protein (261-319AA)

    Isotyp

    IgG
  • Applikationshinweise

    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    Cyclin H (CCNH)

    Andere Bezeichnung

    CCNH

    Hintergrund

    Background: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

    Aliases: 6330408H09Rik antibody, AI661354 antibody, AV102684 antibody, AW538719 antibody, CAK antibody, CAK complex subunit antibody, ccnh antibody, CCNH_HUMAN antibody, CDK activating kinase antibody, CDK activating kinase complex subunit antibody, Cyclin dependent kinase activating kinase antibody, cyclin dependent kinase activating kinase complex subunit antibody, Cyclin H antibody, Cyclin-H antibody, CyclinH antibody, MO15 associated protein antibody, MO15-associated protein antibody, p34 antibody, p36 antibody, p37 antibody

    UniProt

    P51946

    Pathways

    Zellzyklus, Mitotic G1-G1/S Phases, M Phase
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