MAPK11 Antikörper (pThr180, pTyr182)

Produktnummer ABIN710576

Der Kaninchen Polyklonal Anti-MAPK11-Antikörper wurde für WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro) validiert. Er ist geeignet, MAPK11 in Proben von Human zu detektieren.

Kurzübersicht für MAPK11 Antikörper (pThr180, pTyr182) (ABIN710576)

Target: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-MAPK11 Antikörper

Bindungsspezifität: pThr180, pTyr182

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human MAPK11 around the phosphorylation site of Thr180+Tyr182

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu MAPK11

Target: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Andere Bezeichnung: MAPK11+

Hintergrund:

Synonyms: MAPK11phospho T180/Y182, Human p38Beta MAP kinase mRNA complete cds, MAP kinase 11, MAP kinase p38 beta, MAPK 11, Mapk11, Mitogen activated protein kinase 11, Mitogen activated protein kinase p38 2, Mitogen activated protein kinase p38 beta, mitogen-activated protein kinase 11, Mitogen-activated protein kinase p38 beta, MK11_HUMAN, p38 2, p38-2, P38B, p38Beta, P38BETA2, PRKM11, protein kinase mitogen activated 11, SAPK2, SAPK2B, Stress activated protein kinase 2, Stress-activated protein kinase 2.

Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. MAPK11 is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

Gen-ID: 5600

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Response to Water Deprivation, Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Hepatitis C, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteine