Caspase 1 Antikörper (AA 220-415)
Kurzübersicht für Caspase 1 Antikörper (AA 220-415) (ABIN7146933)
Target
Alle Caspase 1 (CASP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 220-415
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Caspase-10 protein (220-415AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IF:1:200-1:500,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Caspase 1 (CASP1)
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Andere Bezeichnung
- CASP1
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Hintergrund
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Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC.
Aliases: ALPS2 antibody, Apoptotic protease Mch-4 antibody, CASP 10 antibody, CASP-10 antibody, CASP10 antibody, CASPA_HUMAN antibody, Caspase 10 apoptosis related cysteine peptidase antibody, Caspase-10 antibody, Caspase-10 subunit p12 antibody, FADD like ICE2 antibody, Fas associated death domain protein antibody, FAS-associated death domain protein interleukin-1B-converting enzyme 2 antibody, FLICE 2 antibody, FLICE2 antibody, ICE like apoptotic protease 4 antibody, ICE-like apoptotic protease 4 antibody, Interleukin 1B converting enzyme 2 antibody, MCH 4 antibody
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UniProt
- Q92851
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Pathways
- Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
Target
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